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Items: 3

1.

Hypoxia and HIF-1α Regulate Collagen Production in Keloids

(Submitter supplied) Keloids are reactive or spontaneous fibroproliferative dermal tumors characterized by the exaggerated and uncontrolled accumulation of extracellular collagen. Current approaches to mitigate keloidogenesis are largely procedural in nature. However, a better understanding of its biological drivers may lead to novel targeted treatments for keloids. Through whole-genome expression analysis, we found that a HIF-1α transcriptional footprint is preferentially upregulated (activation score=2.024; p=1.05E-19) in keloid fibroblasts (KFs) compared to normal dermal fibroblasts (NFs). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL16043
19 Samples
Download data: CEL, CHP
Series
Accession:
GSE145725
ID:
200145725

PubMed Similar studies Analyze with GEO2R

2.

GeneChip® PrimeView™ Human Gene Expression Array (with External spike-in RNAs)

(Submitter supplied) See details from Affymetrix. This is a commercially available chip.
Organism:
Homo sapiens
89 Series
6761 Samples
Download data: CDF, TXT
Platform
Accession:
GPL16043
ID:
100016043

3.

Keloid_fibrobalst_3_rep1

Organism:
Homo sapiens
Source name:
Human primary fibroblast cells_cultured
Platform:
GPL16043
Series:
GSE145725
Download data: CEL, CHP
Sample
Accession:
GSM4331587
ID:
304331587

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db=gds|term=GSM4331587[Accession]|query=1|qty=2|blobid=MCID_669bbb2b57bd0c1190891f01|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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