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Items: 3

1.

A Cas12a ortholog with stringent PAM recognition followed by low off-target editing rates for genome editing

(Submitter supplied) Our study shows that CeCas12a nuclease is active in human cells and the stringency of PAM recognition could be an important factor shaping off-target editing in gene editing. Thus, CeCas12a provides a promising candidate with distinctive characteristics for research and therapeutic applications
Organism:
synthetic construct; Homo sapiens
Type:
Other
Platforms:
GPL11154 GPL15228
195 Samples
Download data: TXT, XLSX
Series
Accession:
GSE146420
ID:
200146420
2.

Illumina HiSeq 2000 (synthetic construct)

Organism:
synthetic construct
48 Series
1879 Samples
Download data
Platform
Accession:
GPL15228
ID:
100015228
3.

lbPAM8min

Organism:
synthetic construct
Source name:
PCR fragments; gene EGFP
Platform:
GPL15228
Series:
GSE146420
Download data
Sample
Accession:
GSM4385260
ID:
304385260

Supplemental Content

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