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Items: 3

1.

Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection [IV]

(Submitter supplied) By CRISPR DNA-fragment editing, in conjunction with chromosome conformation capture, we find that CBSs, if located between enhancers and promoters in the clustered Pcdh and b-globin clusters, function as an enhancer-blocking insulator by forming distinct directional chromatin loops, regardless whether enhancers contain CBS or not. Moreover, computational simulation in silico and genetic deletions in vivo revealed balanced promoter usage in cell populations and stochastic monoallelic expression in single cells by large arrays of tandem variable CBSs. more...
Organism:
Homo sapiens; Mus musculus
Type:
Other
4 related Platforms
358 Samples
Download data: BEDGRAPH
Series
Accession:
GSE138919
ID:
200138919

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
12149 Series
348846 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

3.

4C_HEC-1-B_HS5-1_FWD_mut_rep1

Organism:
Homo sapiens
Source name:
4C_HEC-1-B_HS5-1_FWD_mut
Platform:
GPL16791
Series:
GSE138919
Download data: BEDGRAPH
Sample
Accession:
GSM4404302
ID:
304404302

SRA Run Selector

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db=gds|term=GSM4404302[Accession]|query=2|qty=3|blobid=MCID_6712d114c7d3ca20d5383515|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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