GSM4475147[Accession] - GEO DataSets

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Items: 3

Select item 2001486151.

Molecular and cellular characterization of MDSC differentiated from the bone marrow of Balb/c mice with tumor conditioned media or tumor conditioned media and antagonists for CCR1 and CCR5

(Submitter supplied) Tumor derived factors can promote the differentiation of hematopoietic precursors into suppressive myeloid derived suppressor cells however, the molecular pathways that regulate this differentiation are not fully disclosed. In this study we identified a pathway by which tumor derived factors induce the expression of CCL3 and CCL4 from early HSPCs that autocrinally bind to CCR1 and CCR5 mediate the differentiation of BM cells into suppressive and protumoral cells. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL23092
9 Samples

Download data: CEL

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Accession:: GSE148615

ID:: 200148615

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000230922.

[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array (mogene20st_Mm_ENTREZG_21.0.0)

(Submitter supplied) This Platform is identical to GPL16570 but a custom CDF environment was used to extract data [Brainarray Version 21, mogene20st]. The CDF file can be downloaded using the supplementary file link at the bottom of this record; the CDF and other files can be downloaded at: http://brainarray.mbni.med.umich.edu/Brainarray/Database/CustomCDF/21.0.0/entrezg.asp Protocol: See manufacturer's website (www.affymetrix.com).