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Items: 3

1.

The WDR5 WIN site interactome

(Submitter supplied) The WIN site of WDR5 is a druggable pocket that is crucial for WDR5 protein function and carries therapeutic potential for treating cancer. This study evaluates the protein interactions affected by small molecule blockade of the WIN site of WDR5. We find that PDPK1 directly binds the WIN site of WDR5, and we investigate this newfound interaction through proteomic, biochemical, and genomic methods.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24676 GPL20301
20 Samples
Download data: TXT
2.

Illumina HiSeq 4000 (Homo sapiens)

Platform
Accession:
GPL20301
ID:
100020301
3.

U2OS PDPK1-FKBP(F36V) RNA-seq DMSO rep2 [DMSO-2]

Organism:
Homo sapiens
Source name:
U2OS PDPK1-FKBP(F36V) RNA-seq DMSO
Platform:
GPL20301
Series:
GSE150400
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Sample
Accession:
GSM4548456
ID:
304548456
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