GSM4716610[Accession] - GEO DataSets

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Items: 4

Select item 2001559441.

Massively parallel identification of cis-regulatory variants in yeast promoters

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Escherichia coli; Saccharomyces cerevisiae

Type:: Other

Platforms:: GPL18133 GPL17342
38 Samples

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Series

Accession:: GSE155944

ID:: 200155944

PubMed Full text in PMC Similar studies

Select item 2001559432.

Massively parallel identification of cis-regulatory variants in yeast promoters - Experimental measurements

(Submitter supplied) Sequence variation in regulatory DNA alters gene expression and shapes genetically complex traits. However, the identification of individual, causal regulatory variants is challenging. Here, we used a massively parallel reporter assay to measure the cis-regulatory consequences of 5,832 natural DNA variants in the promoters of 2,503 genes in the yeast Saccharomyces cerevisiae. We identified 451 causal variants, which underlie genetic loci known to affect gene expression. more...