GSM4730285[Accession] - GEO DataSets

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Items: 4

Select item 2001564091.

Age-associated cryptic transcription in mammalian stem cells is linked to permissive chromatin at cryptic promoters

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other; Methylation profiling by high throughput sequencing

Platforms:: GPL16791 GPL17021
52 Samples

Download data: BED, BW, COV, TXT

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Accession:: GSE156409

ID:: 200156409

PubMed Full text in PMC Similar studies

Select item 2001564062.

Age-associated cryptic transcription in mammalian stem cells is linked to permissive chromatin at cryptic promoters (ChIP-Seq)

(Submitter supplied) Suppressing spurious cryptic transcription by a repressive intragenic chromatin state featuring trimethylated lysine 36 on histone H3 (H3K36me3) and DNA methylation is critical for maintaining self-renewal capacity in mouse embryonic stem cells. In yeast and nematodes, such cryptic transcription is elevated with age, and reducing the levels of age-associated cryptic transcription extends yeast lifespan. more...