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Items: 3

1.

KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium

(Submitter supplied) The shear stress-induced transcription factor Krüppel-like factor 2 (KLF2) confers anti-inflammatory properties to endothelial cells through inhibition of activator protein 1, presumably by interfering with MAPK cascades. To gain insight into the regulation of these cascades by KLF2, we used antibody arrays in combination with time-course mRNA micro-array analysis. No gross changes in MAPKs were detected, rather phosphorylation of actin cytoskeleton-associated proteins, including Focal Adhesion Kinase, was markedly repressed by KLF2. more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Protein profiling by protein array
Platforms:
GPL4868 GPL9787
26 Samples
Download data: TXT
Series
Accession:
GSE19412
ID:
200019412
2.

KINEXUS KAM-1.1 kinome array

(Submitter supplied) phospho-protein-specific antibody array Protocol: see manufacturer's website
Organism:
Homo sapiens
1 Series
8 Samples
Download data
Platform
Accession:
GPL9787
ID:
100009787
3.

mock-4 [kinome]

Organism:
Homo sapiens
Source name:
umbilical vein endothelial cells transduced with mock lentivirus
Platform:
GPL9787
Series:
GSE19412
Download data
Sample
Accession:
GSM483215
ID:
300483215
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db=gds|term=GSM483215[Accession]|query=45|qty=2|blobid=MCID_6733b68b5c1af0737477be88|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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