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Items: 4

1.

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array
4 related Platforms
61 Samples
Download data: TXT
Series
Accession:
GSE19492
ID:
200019492
2.

Transcriptional responses of mouse BMM and TEPM to lipopolysaccharide (LPS)

(Submitter supplied) Evolutionary change in gene expression is generally considered to be a major driver of phenotypic differences between species. We investigated innate immune diversification by analyzing inter-species differences in the transcriptional responses of primary human and mouse macrophages to the TLR4 agonist, LPS. Using a custom platform permitting cross-species interrogation coupled with deep sequencing of mRNA 5’ ends, we identified extensive divergence in LPS-regulated orthologous gene expression between humans and mice (24% of orthologs, http://www.macgate.qfab.org). more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL9802
24 Samples
Download data: TXT
Series
Accession:
GSE19490
ID:
200019490
3.

Transcriptional responses of mouse BMM and TEPM to lipopolysaccharide (LPS)

(Submitter supplied) 60-mer spotted oligonucleotide probes. Protocol: See manufacturer's website (www.agilent.com).
Organism:
Mus musculus
2 Series
24 Samples
Download data
Platform
Accession:
GPL9802
ID:
100009802
4.

TEPM-6h LPS-rep1

Organism:
Mus musculus
Source name:
Mouse thioglycollate-elicited peritoneal macrophages stimulated with 10ng/ml S. minnesota lipopolysaccharide for 6h
Platform:
GPL9802
Series:
GSE19490 GSE19492
Download data: TXT
Sample
Accession:
GSM485842
ID:
300485842
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Supplemental Content

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