GEO DataSets

(Submitter supplied) Background: Polybrominated diphenyl ethers are a group of flame-retardant chemicals appearing increasingly in the environment. Their health effects and mechanisms of toxicity are poorly understood.Objectives: We screened for the sensitive effects and mechanisms of toxicity of 2,2 ,4,4 -tetra-bromodiphenyl ether (BDE-47) by analyzing the gene expression profile in rats exposed to doses comparable to human exposure.Methods: Wistar dams were exposed to vehicle or BDE-47 (0.002 and 0.2 mg/kg body weight) every fifth day from gestation day 15 to postnatal day 20 by injections to caudal vein. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS3608

Platform:

GPL6101

18 Samples

Download data: TXT

Analysis of livers of animals exposed to low doses of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) from gestational day 15 to post-natal day 20. Polybrominated diphenyl ethers are flame-retardant chemicals used in consumer products. Results provide insight into the mechanisms of toxicity of BDE-47.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 agent, 3 dose sets

Platform:

GPL6101

Series:

GSE19868

18 Samples

Download data

(Submitter supplied) The RatRef-12 Expression BeadChip includes twelve genome-scale, gene expression microarrays built using Illumina’s multi-sample Array of Arrays format. BeadChip content (22,523 probes per array) was selected from theNational Center for Biotechnology Information (NCBI) Reference Sequence (RefSeq) database. Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...

Organism:

Rattus norvegicus

7 DataSets

140 Series

2934 Samples

Download data: BGX