GSM4972033[Accession] - GEO DataSets

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Items: 4

Select item 2001636951.

Integrated analyses reveal CHD4 mediating establishment and maintenance of latent KSHV chromatin

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Human gammaherpesvirus 8

Type:: Genome binding/occupancy profiling by high throughput sequencing; Other

Platform:: GPL25719
42 Samples

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Series

Accession:: GSE163695

ID:: 200163695

PubMed Full text in PMC Similar studies

Select item 2001630982.

Integrated analyses reveal CHD4 mediating establishment and maintenance of latent KSHV chromatin [CUT&RUN]

(Submitter supplied) lncRNAs regulate protein functions via formation of protein-RNA complexes. Previous studies have shown that expression of viral lncRNA, polyadenylated nuclear RNA (PAN RNA) is essential for inducible viral genomic looping and distal gene activation during Kaposi's sarcoma-associated herpesvirus (KSHV) reactivation. Here we show an underlying molecular mechanism and regulation of KSHV latency by a viral lncRNA-CHD4 (chromodomain helicase DNA binding protein 4) interaction. more...