GEO DataSets

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens; Human gammaherpesvirus 8

Type:

Methylation profiling by genome tiling array; Genome binding/occupancy profiling by genome tiling array

Platform:

GPL9942

19 Samples

Download data: GPR

(Submitter supplied) Herpesvirus latency is generally thought to be governed by epigenetic modifications, but the dynamics of viral chromatin at early timepoints of latent infection are poorly understood. Here, we report a comprehensive spatial and temporal analysis of epigenetic modifications during latent infection with Kaposi's sarcoma associated herpesvirus (KSHV), the etiologic agent of Kaposi's sarcoma and primary effusion lymphoma (PEL). more...

Organism:

Homo sapiens; Human gammaherpesvirus 8

Type:

Genome binding/occupancy profiling by genome tiling array

Platform:

GPL9942

12 Samples

Download data: GPR

(Submitter supplied) Custom high-resolution KSHV microarrays were designed by shifting a sequence window of 60 nt. across both strands of the prototypic type P KSHV sequence (NC_009333) and the terminal repeat unit (KSU86666). Probes with a length between 45 and 60 nucleotides were selected from these windows such that their melting temperature was close to the optimal Tm of 80°C. To also ensure complete coverage of type M KSHV strains, the resulting probesets were aligned to the type M reference sequence (genbank accession NC_003409) and additional probes were designed in an identical manner for all regions which were not already covered by the original probeset. more...

Organism:

Human gammaherpesvirus 8

3 Series

19 Samples

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