GSM5011856[Accession] - GEO DataSets - NCBI

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Items: 3

Select item 2001644781.

Development of a transcriptomic biomarker to detect histone deacetylase inhibitors (HDACi) in TK6 cells

(Submitter supplied) Transcriptomic signatures, or biomarkers, of toxicity can facilitate rapid mechanistic analysis of chemicals using high-content transcriptomic data and identification of potential hazards to human health. We developed an 81-gene transcriptomic biomarker, named TGx-HDACi, to detect histone deacetylase inhibitors (HDACi) in TK6 human lymphoblastoid cells after 4 hours of chemical exposure. This work leveraged an established transcriptomic biomarker of DNA damage, TGx-DDI, which was developed by Heng Hong Li et al. more...

Organism:: Homo sapiens; blank sample

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL29107 GPL18573
128 Samples

Download data: TXT

Series

Accession:: GSE164478

ID:: 200164478

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000185732.

Illumina NextSeq 500 (Homo sapiens)

Organism:: Homo sapiens

12508 Series
341119 Samples

Platform

Accession:: GPL18573

ID:: 100018573

Select item 3050118563.

Sample 21_Non-HDACi_Cisplatin_Rep 3

Organism:: Homo sapiens

Source name:: TK6_Non-HDACi_Cisplatin

Platform:: GPL18573
Series:: GSE164478

Sample

Accession:: GSM5011856

ID:: 305011856

SRA Run Selector

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GSM5011856[Accession] (3)
GEO DataSets
GSM5011859[Accession] (3)
GEO DataSets
cartilage acidic protein 1 isoform 2 precursor [Mus musculus]
cartilage acidic protein 1 isoform 2 precursor [Mus musculus]
gi|1253558226|ref|NP_001343517.1|

Protein
transmembrane protein adipocyte-associated 1 isoform 2 [Mus musculus]
transmembrane protein adipocyte-associated 1 isoform 2 [Mus musculus]
gi|2284291829|ref|NP_001397509.1|

Protein
CCR4-NOT core subunit BTT1 [Saccharomyces cerevisiae S288C]
CCR4-NOT core subunit BTT1 [Saccharomyces cerevisiae S288C]
gi|6320458|ref|NP_010538.1|

Protein

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