GSM5013357[Accession] - GEO DataSets

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Items: 4

Select item 2001645281.

Defining the lineage of thermogenic perivascular adipose tissue

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL21103 GPL24676
42 Samples

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Accession:: GSE164528

ID:: 200164528

PubMed Full text in PMC Similar studies

Select item 2001645272.

Defining the lineage of thermogenic perivascular adipose tissue [PVAT v IWAT]

(Submitter supplied) Brown adipose tissue can expend large amounts of energy and thus increasing its amount or activity is a promising therapeutic approach to combat metabolic disease. In humans, major deposits of brown fat cells are found intimately associated with large blood vessels, corresponding to perivascular adipose tissue (PVAT). However, the cellular origins of PVAT are poorly understood. We applied single cell transcriptomic analyses, ex vivo adipogenesis assays, and genetic fate mapping to determine the identity of perivascular adipocyte progenitors. more...