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Items: 3

1.

Massively parallel characterization of CYP2C9 variant enzyme activity and abundance

(Submitter supplied) CYP2C9 encodes a cytochrome P450 enzyme responsible for metabolizing up to 15% of small molecule drugs, and CYP2C9 variants can alter the safety and efficacy of these therapeutics. In particular, the anti-coagulant warfarin is prescribed to over 15 million people annually and polymorphisms in CYP2C9 can affect patient response leading to an increased risk of hemorrhage. We developed Click-seq, a pooled yeast-based activity assay to test thousands of variants. more...
Organism:
Escherichia coli; Saccharomyces cerevisiae; Homo sapiens
Type:
Other
5 related Platforms
12 Samples
Download data: CSV, TSV
Series
Accession:
GSE165412
ID:
200165412

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Sequel II (Escherichia coli)

Organism:
Escherichia coli
2 Series
8 Samples
Download data
Platform
Accession:
GPL29643
ID:
100029643

3.

CYP2C9_abundance_PacBio_SMRT_cell_2

Organism:
Escherichia coli
Source name:
Synthetic sequence
Platform:
GPL29643
Series:
GSE165412
Download data
Sample
Accession:
GSM5032995
ID:
305032995

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db=gds|term=GSM5032995[Accession]|query=10|qty=4|blobid=MCID_673a32ff4fec062fef79d082|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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