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Items: 3

1.

Universal Toxicity Gene Signatures for Early Identification of Drug-induced Tissue Injuries in Rats

(Submitter supplied) A new safety testing paradigm that relies on gene expression biomarker panels was developed that can easily and quickly identify dose-dependent drug-induced injuries across a number of different tissues in rats prior to drug candidate selection. The resource-sparing approach has yielded positive impact on early compound de-risking, enabling drug advancement in a cost-effective manner while reducing later probability of attrition. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platforms:
GPL3631 GPL15569
222 Samples
Download data: TXT
Series
Accession:
GSE166229
ID:
200166229
2.

Rosetta/Merck Rat 4.0 A1 microarray

(Submitter supplied) Oligonucleotide array on glass. Contains 60-mer probes (60-mer). Protocol: See manufacturer's website (www.agilent.com)
Organism:
Rattus norvegicus
3 Series
215 Samples
Download data
Platform
Accession:
GPL15569
ID:
100015569
3.

US-1046071 vs. Soleus; Day 15; Cerivastatin 0.0mkd; MSDA 025mkd; #038387

Organism:
Rattus norvegicus
Source name:
Soleus; Day 15; Cerivastatin Control Pool (channel 1) Skeletal Muscle (Soleus) (channel 2)
Platform:
GPL15569
Series:
GSE166229
Download data: TXT
Sample
Accession:
GSM5173102
ID:
305173102
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