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Items: 4

1.

Altered costimulatory signaling and hypoxia support chromatin landscapes that limit the functional potential of exhausted T cells in cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19057
117 Samples
Download data: BW
Series
Accession:
GSE175443
ID:
200175443

PubMed Full text in PMC Similar studies

2.

Altered costimulatory signaling and hypoxia support chromatin landscapes that limit the functional potential of exhausted T cells in cancer [RNA-seq]

(Submitter supplied) Increases in terminally exhausted T cells in the tumor are associated with poor responses to immunotherapy, yet the mechanisms that promote progression to terminal exhaustion remain undefined. To understand the effect of epigenetic changes in subsets of tumor-infiltrating CD8+ T cells, we performed RNA-seq to understand changes in gene expression. CD8 T cells were sorted from the murine B16 melanoma tumor using PD1 and Tim3 expression to define four subsets: PD1lo, PD1mid, PD1hi, and PD1hiTim3+. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
40 Samples
Download data: CSV
Series
Accession:
GSE175408
ID:
200175408

PubMed Full text in PMC Similar studies SRA Run Selector

3.

Illumina NextSeq 500 (Mus musculus)

Organism:
Mus musculus
10290 Series
295819 Samples
Download data
Platform
Accession:
GPL19057
ID:
100019057

4.

PD1mid TIL RNAseq 3

Organism:
Mus musculus
Source name:
B16 melanoma tumor
Platform:
GPL19057
Series:
GSE175408 GSE175443
Download data
Sample
Accession:
GSM5333032
ID:
305333032

SRA Run Selector

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db=gds|term=GSM5333032[Accession]|query=6|qty=2|blobid=MCID_6737cd3bbea12f4e7c7f352e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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