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Items: 3

1.

Advancing a Clinically Relevant Perspective of the Clonal Nature of Cancer

(Submitter supplied) We used DNA content-based flow cytometry to distinguish and isolate nuclei from clonal populations in primary tissues from three disparate cancers with variable clinical histories. We then developed a methodology to adapt flow cytometrically purified nuclei samples for use with whole genome technologies including aCGH and next generation sequencing (NGS). Our results demonstrate that selected aberrations in the genomes of distinct clonal populations in each patient create clinically relevant contexts at least with respect to the cancer types profiled in this study.
Organism:
Homo sapiens
Type:
Genome variation profiling by genome tiling array
Platform:
GPL4091
61 Samples
Download data: TXT
Series
Accession:
GSE21660
ID:
200021660
2.

Agilent-014693 Human Genome CGH Microarray 244A (Feature number version)

(Submitter supplied) This microarray is Agilent’s premium product for human DNA copy-number profiling. Over 236,000 60-mer oligonucleotide probes, specifically optimized for copy-number measurement, span coding and non-coding genomic sequences with median spacing of 7.4 kb and 16.5 kb respectively. This microarray is designed for use with Agilent’s optimized assay protocols, enabling researchers to use nanogram levels of total genomic DNA without complexity reduction. more...
Organism:
Homo sapiens
113 Series
1 Related Platform
2690 Samples
Download data
Platform
Accession:
GPL4091
ID:
100004091
3.

P4028

Organism:
Homo sapiens
Source name:
Frozen tissue biopsy (channel 1) Reference pooled 46XX (channel 2)
Platform:
GPL4091
Series:
GSE21660
Download data: TXT
Sample
Accession:
GSM540565
ID:
300540565
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