GEO DataSets

(Submitter supplied) Pseudomonas aeruginosa chronically colonizes the lungs of individuals with CF, where it reaches high cell densities and produces a battery of virulence factors. Upon infection, a single strain of P. aeruginosa can colonize an individual’s lungs throughout his or her lifetime. To understand the evolution of P. aeruginosa during chronic lung infection, we conducted both genotypic and phenotypic analyses on clinical isogenic strains obtained from the lungs of three different individuals with CF. more...

Organism:

Pseudomonas aeruginosa

Type:

Expression profiling by array

Dataset:

GDS4249

Platform:

GPL84

38 Samples

Download data: CEL

Analysis of clonal isolates collected from three patients with cystic fibrosis (CF). The isolates were collected between 3 months to 8 years after colonization, representing upwards of 39,000 in vivo generations. Results provide insight into the molecular basis of long-term infection of CF lung.

Organism:

Pseudomonas aeruginosa

Type:

Expression profiling by array, transformed count, 4 individual, 19 isolate, 3 other, 4 time sets

Platform:

GPL84

Series:

GSE21966

38 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html This GeneChip probe array is a powerful tool for monitoring trascriptional regulation and antimicrobial agent response of P. aeruginosa. The array represents the annotated genome of P. aeruginosa strain PA01 and includes 5,549 protein-coding sequences, 18 tRNA genes, a representative of the ribosomal RNA cluster and 117 genes present in strains other than PA01. more...

Organism:

Pseudomonas aeruginosa

24 DataSets

167 Series

1375 Samples

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