U.S. flag

An official website of the United States government

Format
Sort by

Send to:

Choose Destination

Search results

Items: 3

1.

Metformin affects transcriptomic pathways involved in cell survival, metabolism and angiogenesis in ovarian cancer cells

(Submitter supplied) The objectives of the present study are to determine the effect of metformin on sphere formation, extracellular matrix invasion, and transcriptome profile of ovarian cancer (COVCAR) cells isolated from ascites of chickens that naturally developed ovarian cancer. Our results suggest that metformin treatment significantly decreased sphere formation and invasiveness of COVCAR cells. Pairwise statistical analysis of transcriptomic data using Deseq2 software revealed 0, 4, 365 genes that were differentially expressed (DEGs) in cells treated with 0.5, 1, 2 mM metformin-treated cells compared to controls, respectively.
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19005
16 Samples
Download data: CSV
Series
Accession:
GSE182084
ID:
200182084

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2500 (Gallus gallus)

Organism:
Gallus gallus
145 Series
4590 Samples
Download data
Platform
Accession:
GPL19005
ID:
100019005

3.

C9P3_T4_2.0mM

Organism:
Gallus gallus
Source name:
COVCAR cells designated as C9 in 3rd passage
Platform:
GPL19005
Series:
GSE182084
Download data
Sample
Accession:
GSM5518321
ID:
305518321

SRA Run Selector

Format
Sort by

Send to:

Choose Destination

Supplemental Content

Filters: Manage Filters

db=gds|term=GSM5518321[Accession]|query=2|qty=2|blobid=MCID_671fa4abe158b40557c5f21a|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Important Links

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Genes & Expression > Gene Expression Omnibus (GEO) Datasets
Support Center