U.S. flag

An official website of the United States government

Format
Sort by

Send to:

Choose Destination

Search results

Items: 3

1.

Structural variation at the ZNF558 locus controls a gene regulatory network in human brain development

(Submitter supplied) The human forebrain has expanded in size and complexitycompared to that of chimpanzeedespite limited changesinprotein-coding genes, suggesting that gene regulation is an importantdriver of brain evolution. Here we identify a KRAB-ZFPtranscription factor, ZNF558, that isexpressed in human but not chimpanzee forebrain neural progenitor cells. ZNF558 evolved asa suppressor of LINE-1 transposons but has been co-opted to regulate the mitophagy geneSPATA18, supporting a link between mitochondrial homeostasis andcorticalexpansion. more...
Organism:
Pan troglodytes; Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL24676 GPL21121 GPL18573
71 Samples
Download data: BW, MTX, TAB, TSV, TXT
Series
Accession:
GSE182224
ID:
200182224

PubMed Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Pan troglodytes)

Organism:
Pan troglodytes
12 Series
139 Samples
Download data
Platform
Accession:
GPL21121
ID:
100021121

3.

ciPS_C6_d15_batch1

Organism:
Pan troglodytes
Source name:
ciPS_C6
Platform:
GPL21121
Series:
GSE182224
Download data
Sample
Accession:
GSM5525329
ID:
305525329

SRA Run Selector

Format
Sort by

Send to:

Choose Destination

Supplemental Content

Filters: Manage Filters

db=gds|term=GSM5525329[Accession]|query=1|qty=3|blobid=MCID_67364ca65ff35f4f6715956b|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Important Links

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Genes & Expression > Gene Expression Omnibus (GEO) Datasets
Support Center