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Items: 3

1.

Inherited functional regulatory risk variants for common human cancers [MPRA]

(Submitter supplied) Single nucleotide variants (SNVs) in regulatory DNA are linked to inherited cancer risk. Massively parallel reporter assays (MPRA) of 5,031 SNVs linked to 14 neoplasms comprising >90% of human malignancies were performed in pertinent diploid cell types then integrated with matching chromatin accessibility, looping, and eQTL data to identify 411 regulatory SNVs and their putative target eGenes. The latter highlighted specific protein networks in lifetime cancer risk, including mitochondrial translation, proliferation, signaling, adhesion, and immunity. more...
Organism:
Homo sapiens; synthetic construct
Type:
Other
Platforms:
GPL21697 GPL27609
50 Samples
Download data: FA, TSV
Series
Accession:
GSE183301
ID:
200183301
2.

NextSeq 550 (Homo sapiens)

Platform
Accession:
GPL21697
ID:
100021697
3.

GM12878 MPRA rep 1 [gm_1]

Organism:
Homo sapiens
Source name:
GM12878 MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555251
ID:
305555251
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Supplemental Content

db=gds|term=GSM5555251[Accession]|query=12|qty=3|blobid=MCID_67265f70e8de71654a35c612|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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