GSM5603034[Accession] - GEO DataSets

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Items: 4

Select item 2001850051.

Induction of mouse totipotent stem cells by a defined chemical cocktail

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platform:: GPL24247
18 Samples

Download data: BW, MTX, NARROWPEAK, TSV

Series

Accession:: GSE185005

ID:: 200185005

PubMed Similar studies

Select item 2001850002.

Induction of mouse totipotent stem cells by a defined chemical cocktail [bulk RNA-seq]

(Submitter supplied) We demonstrate induction and long-term maintenance of totipotent stem cells (TotiSCs) from mouse pluripotent stem cells (PSCs) by a combination of three small molecules, TTNPB, 1-Azakenpaullone, and WS6. These cells, which we designated as ciTotiSCs (chemically induced totipotent stem cells), resembled mouse totipotent 2C-embryo stage cells at both transcriptome and epigenome level.