GSM560837[Accession] - GEO DataSets

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Items: 4

Select item 2000226061.

Identification of an SRF- and androgen-dependent gene signature in prostate cancer

(Submitter supplied) The androgen receptor (AR) is the principal target for treatment of non-organ confined prostate cancer (PCa). Systems and bioinformatics approaches suggest that considerable variation exists in the mechanisms by which AR regulates expression of effector genes and point towards a role for secondary transcription factors (TFs) therein. We identified a novel indirect mechanism of androgen action in which effects of androgens on PCa cells are mediated by Serum Response Factor (SRF). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3861
Platform:: GPL570
12 Samples

Download data: CEL

Series

Accession:: GSE22606

ID:: 200022606

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 38612.

Synthetic androgen R1881 effect on transcription factor SRF-deficient prostate cancer cells

Analysis of LNCaP androgen-sensitive prostate adenocarcinoma cells, SRF (serum response factor)-silenced and treated with synthetic androgen R1881. Effects of androgens on prostate cancer (PCa) cells can be mediated by SRF. Results provide insight into targets for androgen action in PCa cells.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent, 2 protocol sets

Platform:: GPL570
Series:: GSE22606
12 Samples

Download data: CEL

DataSet

Accession:: GDS3861

ID:: 3861

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...