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Items: 3

1.

Highly Aneuploid Zebrafish Malignant Peripheral Nerve Sheath Tumors have Genetic Alterations Similar to Human Cancers

(Submitter supplied) Aneuploidy is a hallmark of human cancers, but most mouse cancer models lack the extensive aneuploidy seen in many human tumors. The zebrafish is becoming an increasingly popular model for studying cancer. Here we report that malignant peripheral nerve sheath tumors (MPNSTs) that arise in zebrafish as a result of mutations in either ribosomal protein (rp) genes or in p53 are highly aneuploid. Karyotyping reveals that these tumors frequently harbor near-triploid numbers of chromosomes, and they vary in chromosome number from cell-to-cell within a single tumor. more...
Organism:
Danio rerio
Type:
Genome variation profiling by array; Genome variation profiling by high throughput sequencing
Platforms:
GPL10797 GPL9319
48 Samples
Download data: TXT
2.

Illumina Genome Analyzer II (Danio rerio)

Platform
Accession:
GPL9319
ID:
100009319
3.

Normal tail tissue, specimen "G2_1-2"

Organism:
Danio rerio
Source name:
Tail from adult fish
Platform:
GPL9319
Series:
GSE23666
Download data
Sample
Accession:
GSM587252
ID:
300587252
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db=gds|term=GSM587252[Accession]|query=1|qty=2|blobid=MCID_67236918aac99775972d5098|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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