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Items: 4

1.

Down Syndrome

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing
4 related Platforms
75 Samples
Download data: RESULTS, TAR
Series
Accession:
GSE196447
ID:
200196447
2.

Dyrk1a dosage effects on the transcriptome of embryonic hearts from the Dp1Tyb mouse model of Down syndrome using bulk RNAseq

(Submitter supplied) We performed bulk RNAseq on whole hearts from E13.5 Dp1Tyb embryos and from wild-type littermates, as well as hearts from E13.5 Dp1TybDyrk1a+/+/- embryos and wild-type littermates. Analysis showed the expected increased expression of the Hsa21-orthologous genes on Mmu16 that are present in 3 copies. Gene set enrichment analysis identified pathways that are altered in Dp1Tyb hearts. Some of these changes were dependent on 3 copies of Dyrk1a.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
20 Samples
Download data: TXT
Series
Accession:
GSE196445
ID:
200196445
3.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
4.

LAN326A1_S30_L006

Organism:
Mus musculus
Source name:
Heart
Platform:
GPL17021
Series:
GSE196445 GSE196447
Download data
Sample
Accession:
GSM5884345
ID:
305884345
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Supplemental Content

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