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Items: 3

1.

Mitotic chromosomes are self-entangled and disentangle through a Topoisomerase II-dependent two stage exit from mitosis

(Submitter supplied) The topological state of chromosomes determines their mechanical properties, dynamics, and function. Recent work indicated that interphase chromosomes are largely free of entanglements. Here, we use Hi-C, polymer simulations and multi-contact 3C, and propose that, in contrast, mitotic chromosomes are self-entangled. We explore how a mitotic self-entangled state is converted into an unentangled interphase state during mitotic exit. more...
Organism:
Homo sapiens
Type:
Other
Platforms:
GPL28352 GPL30173 GPL20301
137 Samples
Download data: MCOOL, TXT
Series
Accession:
GSE198610
ID:
200198610

PubMed Similar studies

2.

Illumina HiSeq 4000 (Homo sapiens)

Organism:
Homo sapiens
8491 Series
195008 Samples
Download data
Platform
Accession:
GPL20301
ID:
100020301

3.

DpnII Hi-C on HeLa S3 MR DMSO or ICRF-193 added at different times: 2-7hr DMSO R2

Organism:
Homo sapiens
Source name:
uterine/cervical adenocarcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM5953520
ID:
305953520

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db=gds|term=GSM5953520[Accession]|query=5|qty=2|blobid=MCID_6730cbd4fc33ef41366f7519|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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