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Items: 3

1.

The gene expression profile of CD4 T-cells with STAT3 gain-of-function and loss-of-function mutations

(Submitter supplied) Purpose: Recently discovered activating Interleukin-6 receptor subunit beta (IL6ST, encoding glycoprotein 130 (gp130)) mutations, as well as germline Signal transducer and activator of transcription 3 (STAT3) gain-of-function mutations are associated with multi-organ autoimmunity, severe morbidity, and adverse prognosis, resulting in an unmet medical need. Methods: To decipher the crucial cellular subsets and disease biology associated with STAT3 gain-of-function mutations, we examined the gene expression profile of STAT3 gain-of-function and loss-of-function mutations in unstimulated, IL10- or IL21-stimulated CD4 T cells and compared them to healthy donor cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
29 Samples
Download data: TXT
Series
Accession:
GSE198963
ID:
200198963

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2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
17049 Series
931958 Samples
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Platform
Accession:
GPL24676
ID:
100024676

3.

Q288P_1_1_Unst

Organism:
Homo sapiens
Source name:
Unstimulated STAT3-Q288P CD4+ T-cells
Platform:
GPL24676
Series:
GSE198963
Download data: TXT
Sample
Accession:
GSM5961768
ID:
305961768

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db=gds|term=GSM5961768[Accession]|query=8|qty=2|blobid=MCID_6732a32c711d78546115069e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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