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Items: 3

1.

Loss of tumor-derived SMAD4 enhances primary tumor growth but not metastasis following BMP4 signalling

(Submitter supplied) We have reported previously that in preclinical models, BMP4 is a potent inhibitor of breast cancer metastasis and that high BMP4 protein levels predict favourable patient outcome. Here, we investigated the requirement for functional SMAD4 in mediating the anti-metastatic response of BMP4, given reports of promotion of metastasis by BMP4 in cancers where SMAD4 is frequently deleted. BMP4-induced inhibition of metastasis does not require functional SMAD4 in tumor cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
16 Samples
Download data: TXT
Series
Accession:
GSE199628
ID:
200199628
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

shSmad4.Vc_12

Organism:
Homo sapiens
Source name:
SV12
Platform:
GPL18573
Series:
GSE199628
Download data
Sample
Accession:
GSM5976434
ID:
305976434
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db=gds|term=GSM5976434[Accession]|query=1|qty=2|blobid=MCID_67136a9e84112c3be22e2112|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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