GSM6202509[Accession] - GEO DataSets

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Items: 4

Select item 2002049361.

A combinatorial approach to uncover a novel Integrator subunit

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL30173 GPL18573
40 Samples

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Series

Accession:: GSE204936

ID:: 200204936

PubMed Full text in PMC Similar studies

Select item 2002049322.

A combinatorial approach to uncover a novel Integrator subunit [ChIP-seq I]

(Submitter supplied) The Integrator complex is one of the most elusive transcriptional regulators in metazoans, deemed to be recruited after initiation to help establish and modulate paused RNAPII. Recent structural, biochemical, and functional evidence suggest that Integrator is composed of 14 subunits, assembling, and operating in a modular fashion. We employed proteomics and machine-learning (alphafold2) approaches to discover a novel Integrator subunit, INTS15. more...