GSM6206841[Accession] - GEO DataSets

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Items: 4

Select item 2002052111.

RNA catabolism restricts ERV expression and functionalization

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

Platforms:: GPL24247 GPL24198 GPL21626
90 Samples

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Series

Accession:: GSE205211

ID:: 200205211

PubMed Full text in PMC Similar studies

Select item 2002051752.

RNA catabolism restricts ERV expression and functionalization [Iso-seq]

(Submitter supplied) Endogenous retroviruses (ERVs) are remnants of ancient parasitic viral integrations and comprise a sizable portion of the genome in most organisms. Deregulated expression of ERVs in human is associated with a plethora of disease conditions, such as cancer and neurodegeneration. Epigenetic mechanisms silence most ERVs by generating a local repressive environment (heterochromatin) to prevent their expression. more...