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Items: 3

1.

Remodeling of the Immune and Stromal Cell Compartment by PD-1 Blockade in Mismatch Repair-Deficient Colorectal Cancer

(Submitter supplied) Immune checkpoint inhibitor (ICI) therapy can induce complete responses in mismatch repair-deficient and microsatellite instability-high (d-MMR/MSI-H) colorectal cancers (CRCs). However, the mechanism responsible for pathological complete response (pCR) to immunotherapy has not been completely understood. We utilize single-cell RNA sequencing to examine the immune and stromal cell dynamics in 19 patients with d-MMR/MSI-H CRC treated with the neoadjuvant PD-1 blockade. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL29480 GPL24676
40 Samples
Download data: MTX, TSV
Series
Accession:
GSE205506
ID:
200205506

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2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
14743 Series
880979 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

171: P17, colon, tumor, anti-PD-1, scRNA-seq

Organism:
Homo sapiens
Source name:
colon
Platform:
GPL24676
Series:
GSE205506
Download data: MTX, TSV
Sample
Accession:
GSM6213963
ID:
306213963

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db=gds|term=GSM6213963[Accession]|query=1|qty=2|blobid=MCID_6664375aac4a2c1050dd6d23|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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