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GEO DataSets

Functional Genomics Studies

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Items: 4

Select item 2002096561.

scNMT-seq of the adult NSC lineage - RNA

(Submitter supplied) Stem cells in the adult brain are specialized astrocytes capable of generating neurons and glial cells. While neural stem cells (NSCs) and common astrocytes have clearly distinct functions, they share highly similar transcriptome profiles. How stemness is molecularly encoded is therefore unclear. Here we use single-cell NMT-seq to simultaneously characterize the transcriptome, DNA methylome and chromatin accessibility of astrocytes and the NSC lineage in the healthy and ischemic brain. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL21626 GPL30172
2084 Samples

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Accession:: GSE209656

ID:: 200209656

PubMed Full text in PMC Similar studies

Select item 2002108062.

Single-cell triple-omics uncovers DNA methylation as key feature of stemness in the healthy and ischemic adult brain

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing