GSM642820[Accession] - GEO DataSets

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Items: 4

Select item 2000261771.

Functional evidence that Drosha over-expression in cervical squamous cell carcinoma affects cell phenotype and microRNA profiles

(Submitter supplied) Although gain of chromosome-5p is one of the most frequent DNA copy number imbalances in cervical squamous cell carcinoma (SCC), the genes that drive its selection remain poorly understood. In a previous cross-sectional clinical study we showed that the microRNA processor Drosha (located on chromosome-5p) demonstrates frequent copy-number gain and over-expression in cervical SCC, associated with altered microRNA profiles. more...

Organism:: Human alphaherpesvirus 1; Human alphaherpesvirus 2; Lymphocryptovirus; Homo sapiens; Human betaherpesvirus 5; Rhadinovirus; Betapolyomavirus hominis; JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Betapolyomavirus macacae

Type:: Non-coding RNA profiling by array; Expression profiling by array

Platforms:: GPL570 GPL11338
24 Samples

Download data: CEL, TXT

Series

Accession:: GSE26177

ID:: 200026177

Select item 2000261752.

Functional evidence that Drosha over-expression in cervical squamous cell carcinoma affects cell phenotype and microRNA profiles [miRNA]

(Submitter supplied) Comparison of miRNA expression profiles in cervical carcinoma cell lines to study the effects of Drosha expression levels

Organism:: Human alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; Homo sapiens; Rhadinovirus; Betapolyomavirus hominis; Human alphaherpesvirus 2; Lymphocryptovirus; Merkel cell polyomavirus; JC polyomavirus; Betapolyomavirus macacae

Type:: Non-coding RNA profiling by array

Platform:: GPL11338
18 Samples

Download data: TXT

Series

Accession:: GSE26175

ID:: 200026175

Select item 1000113383.

Exiqon miRCURY LNA microRNA Array, v.8.0 - all organisms (miRBase 14.0)

(Submitter supplied) miRNA annotation based on Sanger miRBase 14.0. LotNumberRange: 1008-1012 Protocol: See manufacturer's website

Organism:: Homo sapiens; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Human betaherpesvirus 5; Lymphocryptovirus; Rhadinovirus; JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Betapolyomavirus hominis; Betapolyomavirus macacae

2 Series
18 Samples

Download data

Platform

Accession:: GPL11338

ID:: 100011338

Select item 3006428204.

Malignant cervical carcinoma cell line; manipulated_MS751.pcDNA3.1.zeo.Drosha #1

Organism:: Homo sapiens

Source name:: Cluster 1: Drosha under-expressing cell line: construct to over-express Drosha in MS751 cell line; levels only reached 1.996x reference; miRNA profiles still clustered with Drosha under-expressing samples; replicate 1 (channel 1) First Choice Human RNA Survey Panel, Ambion, Austin, TX (channel 2)