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Items: 4

1.

DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Methylation profiling by genome tiling array
4 related Platforms
72 Samples
Download data: IDAT, TXT
Series
Accession:
GSE210763
ID:
200210763
2.

DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon [Array]

(Submitter supplied) Genetic variants in the DNMT3A locus have been associated with inflammatory bowel disease (IBD). DNMT3A is part of the epigenetic machinery physiologically involved in DNA methylation. We show that DNMT3A plays a critical role in maintaining intestinal homeostasis and gut barrier function. DNMT3A expression is downregulated in intestinal epithelial cells (IECs) from IBD patients and upon TNF treatment in murine intestinal organoids. more...
Organism:
Homo sapiens; Mus musculus
Type:
Methylation profiling by genome tiling array
Platforms:
GPL31950 GPL21145
48 Samples
Download data: IDAT
Series
Accession:
GSE210721
ID:
200210721
3.

Infinium MouseMethylation285 BeadChip

(Submitter supplied) https://support.illumina.com//array/array_kits/infinium-mouse-methylation-beadchip-kit.html
Organism:
Mus musculus
22 Series
487 Samples
Download data
Platform
Accession:
GPL31950
ID:
100031950
4.

Dnmt3aVillin667, DNA

Organism:
Mus musculus
Source name:
epithelial crypts
Platform:
GPL31950
Series:
GSE210721 GSE210763
Download data: IDAT
Sample
Accession:
GSM6436772
ID:
306436772
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Supplemental Content

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