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Items: 4

1.

BAF complex maintains glioma stem cells in pediatric H3K27M-glioma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL20301 GPL18573
1758 Samples
Download data: BW, CSV
Series
Accession:
GSE212786
ID:
200212786
2.

BAF complex maintains glioma stem cells in pediatric H3K27M-glioma [scRNA-seq]

(Submitter supplied) Diffuse midline gliomas (DMGs) are uniformly fatal pediatric central nervous system cancers, refractory to standard of care therapeutic modalities. The primary genetic drivers are a set of recurrent amino acid substitutions in genes encoding histone H3 (H3.3 and H3.1, K27M), which are currently undruggable. These H3K27M oncohistones perturb normal chromatin architecture, resulting in an aberrant epigenetic landscape, which we interrogated here for epigenetic dependencies using a CRISPR screen in patient-derived H3K27M-glioma neurospheres. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
1728 Samples
Download data: CSV
Series
Accession:
GSE212782
ID:
200212782
3.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
4.

scRNAseq_BT869_AAVS1ko_d4_rep2_cell5

Organism:
Homo sapiens
Source name:
BT869
Platform:
GPL18573
Series:
GSE212782 GSE212786
Download data
Sample
Accession:
GSM6550806
ID:
306550806
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Supplemental Content

db=gds|term=GSM6550806[Accession]|query=3|qty=2|blobid=MCID_670f4333c7d3ca20d521a959|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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