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Items: 4

1.

A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Danio rerio; Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL21741 GPL20301 GPL20828
40 Samples
Download data: NARROWPEAK, TSV
Series
Accession:
GSE213360
ID:
200213360
2.

A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma [ChIP-seq]

(Submitter supplied) Developmental signaling pathways associated with growth factors such as TGFb are commonly dysregulated in melanoma. Here we identified a human TGFb enhancer that was specifically activated in melanoma cells treated with TGFB1 ligand. We generated stable transgenic zebrafish with this enhancer driving green fluorescent protein (TIE:EGFP). EGFP was not expressed in normal melanocytes or early melanomas but was expressed in spatially distinct regions of mature melanomas. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL20301
16 Samples
Download data: NARROWPEAK
Series
Accession:
GSE213326
ID:
200213326
3.

Illumina HiSeq 4000 (Homo sapiens)

Platform
Accession:
GPL20301
ID:
100020301
4.

TGFB1 stimulated A375 Smad2/3 6.11.18

Organism:
Homo sapiens
Source name:
A375 Cells
Platform:
GPL20301
Series:
GSE213326 GSE213360
Download data: NARROWPEAK
Sample
Accession:
GSM6579003
ID:
306579003
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Supplemental Content

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