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Items: 3

1.

Exclusion of m6A from splice-site-proximal regions by the exon-junction complex dictates m6A topologies and mRNA stability

(Submitter supplied) N6-methyladenosine (m6A), a widespread destabilizing mark on mRNA, is non-uniformly distributed across the transcriptome, yet the basis for its selective deposition is unknown. Here, we uncover that m6A deposition is not selective. Instead, m6A distribution is exclusion-based: m6A-consensus harboring sites are methylated by default, unless they are within a window of up to ~200 nt from an exon-intron junction. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24676 GPL24247
250 Samples
Download data: BED, CSV, RDATA, RDS, XLSX
Series
Accession:
GSE204980
ID:
200204980
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

mutant_rep1_IP_additional

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL24676
Series:
GSE204980
Download data: RDS
Sample
Accession:
GSM6601471
ID:
306601471
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db=gds|term=GSM6601471[Accession]|query=3|qty=3|blobid=MCID_664ec684faf6612e8f27d6d6|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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