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Items: 4

1.

DNA methylation as a therapeutic target in RB1 deficient and neuroendocrine prostate cancer and rational co-targeting with B7-H3

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platforms:
GPL24676 GPL20301 GPL16791
31 Samples
Download data: TXT
Series
Accession:
GSE216054
ID:
200216054

PubMed Full text in PMC Similar studies

2.

DNA methylation as a therapeutic target in RB1 deficient and neuroendocrine prostate cancer and rational co-targeting with B7-H3 [RNA-Seq 1]

(Submitter supplied) Aberrant DNA methylation has been implicated as a key driver of prostate cancer lineage plasticity and histologic transformation to neuroendocrine prostate cancer (NEPC). DNA methyltransferases (DNMT) are highly expressed, and global DNA methylation levels are elevated in NEPC. We identified that deletion of DNMT genes decreases expression of neuroendocrine lineage markers and markedly reduced NEPC tumor development and metastasis in vivo. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20301
9 Samples
Download data: TXT
Series
Accession:
GSE216052
ID:
200216052

PubMed Full text in PMC Similar studies Analyze with GEO2R

3.

Illumina HiSeq 4000 (Homo sapiens)

Organism:
Homo sapiens
8450 Series
193310 Samples
Download data
Platform
Accession:
GPL20301
ID:
100020301

4.

PM154, Control, rep1

Organism:
Homo sapiens
Source name:
PM154
Platform:
GPL20301
Series:
GSE216052 GSE216054
Download data
Sample
Accession:
GSM6657918
ID:
306657918

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db=gds|term=GSM6657918[Accession]|query=21|qty=2|blobid=MCID_67142546c7d3ca20d5686f4d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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