GSM6675533[Accession] - GEO DataSets

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Items: 4

Select item 2002071161.

Response of cohesin STAG1 and STAG2 to reduction of NIPBL levels

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

Platform:: GPL21697
36 Samples

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Series

Accession:: GSE207116

ID:: 200207116

PubMed Full text in PMC Similar studies

Select item 2002071132.

Response of cohesin STAG1 and STAG2 to reduction of NIPBL levels [ChIP-Seq]

(Submitter supplied) Cohesin mediates sister chromatid cohesion and organizes the genome through the formation of chromatin loops. Two versions of the complex carrying either STAG1 or STAG2 show overlapping and specific functions and both are required to fulfill embryonic development. Cohesin-STAG1 displays longer residence time on chromatin that depends on CTCF and ESCO1 and establishes longer, long-lived chromatin loops together with CTCF. more...