GSM6879583[Accession] - GEO DataSets

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Items: 4

Select item 2002215091.

RNA-Seq data of ruminal epithelial tissue and 16S rRNA sequencing data of rumen digesta in goats infusion of three short-chain fatty acids

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Capra hircus

Type:: Expression profiling by high throughput sequencing; Other

Platforms:: GPL32968 GPL32967
36 Samples

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Accession:: GSE221509

ID:: 200221509

Select item 2002215072.

RNA-Seq data of ruminal epithelial tissue and 16S rRNA sequencing data of rumen digesta in goats infusion of three short-chain fatty acids [RNA-seq]

(Submitter supplied) Emerging data has highlighted the importance of short-chain fatty acids (SCFAs), particularly butyrate, in regulating ruminal homeostasis in vivo isolated epithelial cells. However, little is known about other SCFAs like acetate or propionate, and the interaction between rumen microbes and epithelial immunity are rarely reported. Here, we firstly combined infusion of three SCFAs, to study their different roles in ruminal development, antioxidant capacity, barrier functions, and immunity, as well as cross-talk with ruminal microbiome (16S rRNA sequencing data of rumen digesta) and derived transcriptome (RNA-Seq) and metabolism using an in vivo goat model.