GSM6928878[Accession] - GEO DataSets

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Items: 4

Select item 2002226871.

Clonal evolution of the 3D chromatin landscape of relapsed ALL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL24676
74 Samples

Download data: BED, BEDGRAPH, BW, HIC

Series

Accession:: GSE222687

ID:: 200222687

PubMed Full text in PMC Similar studies

Select item 2002226792.

Clonal evolution of the 3D chromatin landscape of relapsed ALL [Hi-C]

(Submitter supplied) Relapsed pediatric B-cell acute lymphoblastic leukemia (B-ALL) remains one of the leading causes of cancer mortality in children. Up to 20% of children will suffer relapse and face a poor prognosis. Our recent work on the evolution of the epigenetic landscape from diagnosis to relapse demonstrates both substantial diversity in the chromatin landscape as well as shared relapse-specific superenhancer activation, highlighting the importance of chromatin changes in disease progression. more...