GSM6933127[Accession] - GEO DataSets

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Items: 4

Select item 2002228441.

DNMT3B supports meso-endoderm differentiation from mouse embryonic stem cells [scRNA-seq II]

(Submitter supplied) The correct establishment of DNA methylation patterns during mouse early development is essential for cell fate specification. However, the molecular targets as well as the mechanisms that determine the specificity of the de novo methylation machinery during differentiation are not completely elucidated. Here we show that the DNMT3B-dependent DNA methylation in epiblasts of key developmental regulatory regions provides an epigenetic priming that ensures flawless commitment at later stages. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19057
965 Samples

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Accession:: GSE222844

ID:: 200222844

PubMed Full text in PMC Similar studies

Select item 2001684152.

DNMT3B supports meso-endoderm differentiation from mouse embryonic stem cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing