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Items: 4

1.

ScRNA-seq of immune cells in tumors or during EAE from Pglyrp1 KO and wildtype mice.

(Submitter supplied) PGLYRP1 is highly co-expressed with known co-inhibitory molecules and might be a promising novel target for immunotherapy. Indeed, genetic deletion of PGLYRP1 in mice led to decreased tumor growth and an increased activation/effector phenotype in CD8+ T cells, suggesting an inhibitory function of PGLYRP1 in CD8+ T cells. Surprisingly, genetic deletion of PGLYRP1 strongly protected against experimental autoimmune encephalomyelitis (EAE), a model of autoimmune disease in the central nervous system (CNS). more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
30 Samples
Download data: CSV, MTX, RDS, TSV
Series
Accession:
GSE223873
ID:
200223873

2.

Targeting PGLYRP1 promotes anti-tumor immunity while inhibiting autoimmunity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL19057
38 Samples
Download data: CSV, MTX, TSV
Series
Accession:
GSE223896
ID:
200223896

3.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
14094 Series
691744 Samples
Download data
Platform
Accession:
GPL24247
ID:
100024247

4.

KO_Tum_2_FBC

Organism:
Mus musculus
Source name:
MC38-OVA colon carcinoma
Platform:
GPL24247
Series:
GSE223873 GSE223896
Download data: CSV
Sample
Accession:
GSM6998215
ID:
306998215

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db=gds|term=GSM6998215[Accession]|query=21|qty=2|blobid=MCID_671f8ef43b96c123901b14b8|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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