GSM7273561[Accession] - GEO DataSets

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Items: 4

Select item 2002314061.

IRF8 defines the epigenetic landscape in postnatal microglia, thereby directing their transcriptome programs

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platforms:: GPL21493 GPL19057 GPL13112
72 Samples

Download data: COV, MTX, TAB, TSV, TXT

Series

Accession:: GSE231406

ID:: 200231406

PubMed Full text in PMC Similar studies

Select item 2002314042.

Genome-wide methylated CpG status in WT and IRF8KO microglia [WGBS]

(Submitter supplied) The role of the lineage-determining transcription factor, Interferon regulatory factor (IRF8), in microglia remains elucidated. We report the genome-wide methyl-CpG status in adult wild-type (WT) and IRF8-knockout (IRF8KO) microglia by whole-genome bisulfite-Seq (WGBS). Deep-sequencing and subsequent differential analysis revealed that IRF8KO microglia exhibited a cell-intrinsic methylation profile. more...