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Items: 4

1.

Interferon subverts an AHR-JUN axis to promote CXCL13+ T cells in lupus

(Submitter supplied) SLE is prototypical autoimmune disease driven by pathologic T cell-B cell interactions. Expansion of B cell-helper T cells including T follicular helper (Tfh) and T peripheral helper (Tph) cells is a prominent feature of systemic lupus erythematosus (SLE). Human Tfh and Tph cells characteristically produce high levels of the B cell chemoattractant CXCL13, yet regulation of T cell CXCL13 production and the relationship between CXCL13+ T cells and other T cell states remains unclear. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL16791
76 Samples
Download data: BED, BW
Series
Accession:
GSE233050
ID:
200233050
2.

Interferon subverts an AHR-JUN axis to promote CXCL13+ T cells in lupus [JUN AHR modulation]

(Submitter supplied) SLE is prototypical autoimmune disease driven by pathologic T cell-B cell interactions. Expansion of B cell-helper T cells including T follicular helper (Tfh) and T peripheral helper (Tph) cells is a prominent feature of systemic lupus erythematosus (SLE). Human Tfh and Tph cells characteristically produce high levels of the B cell chemoattractant CXCL13, yet regulation of T cell CXCL13 production and the relationship between CXCL13+ T cells and other T cell states remains unclear. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL16791
16 Samples
Download data: BED, BW, CSV
Series
Accession:
GSE233047
ID:
200233047
3.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
4.

CD4_mem_TCDD_JUN_CnR_Rep4

Organism:
Homo sapiens
Source name:
primary CD4+ memory T cells
Platform:
GPL16791
Series:
GSE233047 GSE233050
Download data: BED, BW
Sample
Accession:
GSM7400911
ID:
307400911

Supplemental Content

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