U.S. flag

An official website of the United States government

Format
Sort by

Send to:

Choose Destination

Search results

Items: 4

1.

Mesothelioma tumor aCGH profiles

(Submitter supplied) Malignant pleural mesotheliomas (MPMs) often show CDKN2A and NF2 inactivation but other highly recurrent mutations have not been described. To identify additional driver genes, we used an integrated genomic analysis of 53 MPM tumor samples to guide a focused sequencing effort that uncovered somatic inactivating mutations in BAP1 in 23% of MPM. The BAP1 nuclear deubiquitinase is known to target histones (together with ASXL1 as a Polycomb repressor subunit) and the HCF1 transcriptional co-factor, and we show that BAP1 knockdown in MPM cell lines affects E2F and Polycomb target genes. more...
Organism:
Homo sapiens
Type:
Genome variation profiling by genome tiling array
Platform:
GPL9128
53 Samples
Download data: PDF, TXT
Series
Accession:
GSE29902
ID:
200029902
2.

The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome variation profiling by SNP array; SNP genotyping by SNP array; Genome variation profiling by genome tiling array
Platforms:
GPL3718 GPL96 GPL9128
131 Samples
Download data: CEL, CHP, TXT
Series
Accession:
GSE29211
ID:
200029211
3.

Agilent-014693 Human Genome CGH Microarray 244A (Probe name version)

(Submitter supplied) This microarray is Agilent’s premium product for human DNA copy-number profiling. Over 236,000 60-mer oligonucleotide probes, specifically optimized for copy-number measurement, span coding and non-coding genomic sequences with median spacing of 7.4 kb and 16.5 kb respectively. This microarray is designed for use with Agilent’s optimized assay protocols, enabling researchers to use nanogram levels of total genomic DNA without complexity reduction. more...
Organism:
Homo sapiens
65 Series
1 Related Platform
2165 Samples
Download data
Platform
Accession:
GPL9128
ID:
100009128
4.

A108

Organism:
Homo sapiens
Source name:
Mesothelioma tumor, epi (channel 1) Promega normal reference (channel 2)
Platform:
GPL9128
Series:
GSE29211 GSE29902
Download data: TXT
Sample
Accession:
GSM740350
ID:
300740350
Format
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GSM740350[Accession]|query=1|qty=2|blobid=MCID_669e42d157bd0c1190b042a9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center