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Items: 4

1.

CDK12 prevents MYC-induced transcription-replication conflicts

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL24676 GPL18573 GPL11154
48 Samples
Download data: BED, BW
Series
Accession:
GSE236553
ID:
200236553
2.

CDK12 prevents MYC-induced transcription-replication conflicts [RNA-seq]

(Submitter supplied) In order to identify genes and pathways necessary to preserve genome integrity upon Myc over-expression, we conducted a large siRNA-based screen in isogenic lines. We discovered several genes that suppressed the Myc-induced DNA-damage response and that were essential for the cell survival upon Myc activation. We idntified CDK12, a cyclin dependent kinase involved in transcriptional control and genome stability. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
14 Samples
Download data: BW, XLS
Series
Accession:
GSE236545
ID:
200236545
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

RNA_seq_siLuc_OHT_rep1

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549759
ID:
307549759
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Supplemental Content

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