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Items: 3

1.

Spatiotemporal single-cell analysis decodes cellular dynamics underlying different responses to immunotherapy in Colorectal Cancer

(Submitter supplied) Expanding the efficacy of immune checkpoint blockade (ICB) in colorectal cancer (CRC) patients presses for a comprehensive understanding of treatment responsiveness. Here, we analyzed 169 single-cell samples from CRC patients at multiple sequential time points during the course of anti-PD-1 neoadjuvant therapy to map the evolution of local and systemic immunity. In tumors, exhausted T (Tex) cells or tumor-reactive-like CD8 T (Ttr-like) cells were closely related to treatment efficacy, and we observed correlated dynamics between Tex cells and multiple other tumor-enriched cell types following the treatment. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL24676
169 Samples
Download data: MTX, TSV, TXT
Series
Accession:
GSE236581
ID:
200236581

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2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
17049 Series
931958 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

P02-T-II

Organism:
Homo sapiens
Source name:
Tumor
Platform:
GPL24676
Series:
GSE236581
Download data
Sample
Accession:
GSM7558349
ID:
307558349

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db=gds|term=GSM7558349[Accession]|query=2|qty=2|blobid=MCID_6732073e4322b4744263fa09|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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