GSM7670068[Accession] - GEO DataSets

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Select item 2002396941.

G-quadruplex on Chromosomal DNA Negatively Regulates Topoisomerase 1 Activity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL24676 GPL20795
13 Samples

Download data: BIGWIG

Series

Accession:: GSE239694

ID:: 200239694

PubMed Full text in PMC Similar studies

Select item 2002396922.

G-quadruplex on Chromosomal DNA Negatively Regulates Topoisomerase 1 Activity [ChIP-seq]

(Submitter supplied) Human DNA topoisomerase 1 (Top1) is a crucial enzyme responsible for alleviating torsional stress on DNA during transcription and replication, thereby maintaining genome stability. Previous researches had found that non-working Top1 interacted extensively with chromosomal DNA in human cells. However, the reason for its retention on chromosomal DNA remained unclear. In this study, we discovered a close association between Top1 and chromosomal DNA, specifically linked to the presence of G-quadruplex (G4) structures. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL20795
4 Samples

Download data: BIGWIG

Series

Accession:: GSE239692

ID:: 200239692

PubMed Full text in PMC Similar studies

Select item 1000207953.

HiSeq X Ten (Homo sapiens)

Organism:: Homo sapiens

2075 Series
35706 Samples

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Platform

Accession:: GPL20795

ID:: 100020795

Select item 3076700684.

Replicate 1 of G4P ChIP-seq in HCT116, ChIP enriched reads

Organism:: Homo sapiens

Source name:: colon cancer tissue

Platform:: GPL20795
Series:: GSE239692 GSE239694

Download data: BIGWIG

Sample

Accession:: GSM7670068

ID:: 307670068

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GSM7670068[Accession] (4)
GEO DataSets
PREDICTED: Homo sapiens prospero homeobox 1 (PROX1), transcript variant X4, mRNA
PREDICTED: Homo sapiens prospero homeobox 1 (PROX1), transcript variant X4, mRNA
gi|2217269269|ref|XM_011509771.2|

Nucleotide
reticulon-4 isoform A [Mus musculus]
reticulon-4 isoform A [Mus musculus]
gi|34610235|ref|NP_918943.1|

Protein
Ammotragus lervia isolate ASK14306 D-loop, partial sequence; mitochondrial
Ammotragus lervia isolate ASK14306 D-loop, partial sequence; mitochondrial
gi|2231826367|gb|MZ508001.1|

Nucleotide
adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform 1 [Homo sapiens]
adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform 1 [Homo sapiens]
gi|1635381429|ref|NP_001357405.1|

Protein

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